Tokyo is consistently the most expensive city in Japan and naturally the costs incurred in setting up a business in Japan are also highest in Tokyo. On the other hand, Osaka has a lower cost of living and the Japanese government estimates the expenses associated with establishing a business in Osaka are around 85% of what it would cost in Tokyo. These extra savings can be funneled back into the business while enjoying the many business connections and easy transportation to other commercial hubs that living in Osaka provides.